週次 |
日期 |
單元主題 |
第1週 |
2/22 |
Introduction of Epigenetics, programming and reprogramming |
第2週 |
2/29 |
Extended discussion in Epigenetics, programming and reprogramming |
第3週 |
3/07 |
Transgenerational epigenetic reprogramming (I): Focusing on retrotransposon silencing |
第4週 |
3/14 |
Transgenerational epigenetic reprogramming (II): Focusing on genomic imprinting |
第5週 |
3/21 |
Guided discussion I: Transgenerational reprogramming in germ cells and preimplantation embryos |
第6週 |
3/28 |
Somatic Cell Nuclear Transfer (Animal Cloning):
An extreme example of artificial reprogramming |
第7週 |
4/04 |
Induced pluripotent stem cells and Trans-differentiation |
第8週 |
4/11 |
Guided discussion II: Experimental reprogramming |
第9週 |
4/18 |
Open book midterm exam (30%) |
第10週 |
4/25 |
Review of the midterm question set
(Prof. SS Lin: The application of next generation sequencing in the understanding of RNA biology) |
第11週 |
5/02 |
Epigenetic regulators and Reprogramming: Extended reading |
第12週 |
5/09 |
The roles of functional non-coding RNAs: Extended reading |
第13週 |
5/16 |
Selection of final report topics
The interactions among the 3 levels of epigenetic regulatory machineries |
第14週 |
5/23 |
(Guided discussion)Epigenetics, programming,reprogramming and their implications in diseases and regeneration medicine |
第15週 |
5/30 |
An example of physiological reprogramming: 蠑螈
(Salamandra salamandra) by Prof. Ben Lee |
第16週 |
6/06 |
Students' Final presentation I |
第17週 |
6/13 |
Students' Final presentation II |